Gor Mahia striker Tito Okelo was in action as South Sudan fell 0-1 to Uganda in a Group B contents staged in Kampala on Thursday afternoon.
A resilient South Sudan fell to a late goal by substitute Halid Lwaliwa who headed home a Farouk Miya free kick in the 86th minute.
The game also saw a Cranes debut for Elvis Bwomono who plays in the third tier of English football for Southend United, the 21-year-old defender was born in Uganda but moved to the United Kingdom as a child.
The result means Uganda have seven points from their opening three Group B games while South Sudan remain pointless; the two teams set to face each other at Nyayo Stadium on Monday. The game moved from Juba as the stadium there is being renovated.
Uganda is second in the group on goal difference, below leaders Burkina Faso who managed a 3-1 win over Malawi in a late kick-off in Ouagadougou.
In other games, Rwanda held Cape Verde to a scoreless draw away from home with West Ham striker Sebastien Haller scoring on his Ivory Coast debut.
Uganda 1-0 South Sudan (Grp B)
Cameroon 4-1 Mozambique (Grp F)
Cape Verde 0-0 Rwanda (Grp F)
Congo 2-0 Eswatini (Grp I)
Ghana 2-0 Sudan (Grp C)
Ivory Coast 2-1 Madagascar (Grp K)
Zambia 2-1 Botswana (Grp H)
Algeria 3-1 Zimbabwe (Grp H)
Burkina Faso 3-1 Malawi (Grp B)
Gabon 2-1 The Gambia (Grp D)
Libya 2-3 Equatorial Guinea (Grp J)
Guinea 1-0 Chad (Grp A)
Kenya 1-1 Comoros (Grp G)
Mauritania 1-1 Burundi (Grp E)
Senegal 2-0 Guinea Bissau (Grp I)